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Additional safety unknowns include long-term effects on organ systems where HGF/c-Met signaling plays regulatory roles (liver, kidney, cardiovascular system), potential reproductive toxicity, and effects in individuals with pre-existing neoplastic conditions

The present study, for the first time, demonstrates an underlying mechanism for the activation of eNOS by BPC 157 on stimulating the Cav-1 phosphorylation and reducing the binding of eNOS to Cav-1

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FEMS Microbiol Lett 220(2):255260

Ng, Journal (Endocrinology, Volume 142, Issue 12, December 2001, Pages 51825189)